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Point Mutation Antibodies
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Anti-GNAQ (Q209P) Mouse Monoclonal Antibody
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TD-263291
TD-263292
  • Catalog： TD-26329
  • Clonality： mAb
  • Application： ELISA, WB, IHC
  • Synonyms： Gαq(Q209P)
  • Specification：
    100ul
  • Prices：
    ¥4800
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Anti-GNAQ (Q209P) Mouse Monoclonal Antibody

Cat. #:  TD-26329
Gene Symbol:  GNAQ, CMC1, G-ALPHA-q, GAQ, SWS
Description:   Anti-GNAQ(Q209P) Mouse Monoclonal Antibody
Background:   GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation.
Immunogen:    A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209P, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes Gαq(Q209P) mutant, but not wild type GNAQ of vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing

Western blot:  

TD-263291.jpg
 

Western blot analysis of recombinant GNAQ(Q209P) and wild type proteins. Purified His-tagged GNAQ(Q209P) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-GNAQ(Q209P) monoclonal antibody (Cat. #TD-26329).

Immunofluorescence::  

TD-263292.jpg
 

Immunofluorescence of cells expressing GNAQ proteins with Anti-GNAQ(Q209P) antibody.

HEK293T cells were transfected with pCDNA3-GFP-GNAQ(Q209P) plasmid, pCDNA3-GFP-GNAQ (WT) plasmid, pCDNA3-GFP-GNAQ (Q209L) plasmid or pCDNA3-GFP-GNAQ (Q209R) plasmid, then fixed and stained with Anti-GNAQ(Q209P) monoclonal antibody (Cat. #TD-26329).