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CD Antibodies
Products
Products
CD268
All
ELISA
WB
FCM
- Catalog： TD-31414
- Clonality： mAb
- Application： WB, FCM
- Synonyms： TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin
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Specification：
100ul 50ul
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Prices：
¥2180
Customized service consulting
Mouse Monoclonal Antibody to CD268
| Description | |
| B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. | |
| Specification | |
| Aliases | TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin |
| Entrez GeneID | 115650 |
| Swissprot | Q96RJ3 |
| clone | 5A9B6 |
| WB Predicted band size | 18.9kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | Purified recombinant fragment of human CD268 (AA: extra 1-78) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CD268 mouse mAb against C6 (1) cell lysate.
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Flow cytometric analysis of Raji cells using CD268 mouse mAb (green) and negative control (red).
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