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CD Antibodies
Products
Products
CD258
All
ELISA
IF
FCM
- Catalog： TD-32021
- Clonality： mAb
- Application： IF, FCM
- Synonyms： TNFSF14; LTg; HVEML; LIGHT
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Specification：
100ul 50ul
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Prices：
¥2180
Customized service consulting
Mouse Monoclonal Antibody to CD258
| Description | |
| The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. |
|
| Specification | |
| Aliases | TNFSF14; LTg; HVEML; LIGHT |
| Entrez GeneID | 8740 |
| Swissprot | O43557 |
| clone | 1F4A5 |
| WB Predicted band size | 26.3kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD258 (AA: extra 59-240) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Immunofluorescence analysis of Hela cells using CD258 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of THP-1 cells using CD258 mouse mAb (green) and negative control (red).
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