CH
CD Antibodies
CD197
All
ELISA
WB
FCM
FCM
  • CatalogTD-31345
  • ClonalitymAb
  • Application FCM, ELISA, WB
  • SynonymsBLR2; EBI1; CCR-7; CCR7; CDw197; CMKBR7; CC-CKR-7
  • Specification
    100ul 50ul
  • Prices
    ¥2180
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Mouse Monoclonal Antibody to CD197


Description
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
Specification
Aliases BLR2; EBI1; CCR-7; CCR7; CDw197; CMKBR7; CC-CKR-7
Entrez GeneID 1236
Swissprot P32248
clone 4B7B8
WB Predicted band size 42.9kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD197 (AA: extra mix) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CD197 mouse mAb against C6 (1) cell lysate.
 
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Flow cytometric analysis of HL-60 cells using CD197 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of K562 cells using CD197 mouse mAb (green) and negative control (red).