CH
CD Antibodies
CD193
All
ELISA
FCM
FCM
  • CatalogTD-31332
  • ClonalitymAb
  • Application FCM
  • SynonymsCKR3; CCR3; CMKBR3; CC-CKR-3
  • Specification
    100ul 50ul
  • Prices
    ¥2180
Customized service consulting

Mouse Monoclonal Antibody to CD193


Description
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
Specification
Aliases CKR3; CCR3; CMKBR3; CC-CKR-3
Entrez GeneID 1232
Swissprot P51677
clone 8E9H10
WB Predicted band  size 41kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD193 (AA: extra mix) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-313321.jpg

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

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Flow cytometric analysis of HL-60 cells using CD193 mouse mAb (green) and negative control (red).
TD-313323.jpg
Flow cytometric analysis of K562 cells using CD193 mouse mAb (green) and negative control (red).