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CD Antibodies
Products
Products
CD174
All
ELISA
FCM
- Catalog： TD-31638
- Clonality： mAb
- Application： FCM
- Synonyms： FUT3; LE; Les; FT3B; FucT-III
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Specification：
100ul 50ul
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Prices：
¥2180
Customized service consulting
Mouse Monoclonal Antibody to CD174
| Description | |
| The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] |
|
| Specification | |
| Aliases | FUT3; LE; Les; FT3B; FucT-III |
| Entrez GeneID | 2525 |
| Swissprot | P21217 |
| clone | 1F8G5C7 |
| WB Predicted band size | 42.1kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD174 (AA: 199-361) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of HL-60 cells using CD174 mouse mAb (green) and negative control (red).
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