Mouse Monoclonal Antibody to CD14
|
Description |
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is ob/served on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages. |
Specification |
Aliases |
CD14 |
Entrez GeneID |
929 |
Swissprot |
P08571 |
clone |
5A3 |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD14 expressed in E. Coli. |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Application |
IHC |
1/200 - 1/1000 |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |