Mouse Monoclonal Antibody to CD3E
|
Description |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
Specification |
Aliases |
T3E; TCRE; FLJ18683; CD3E |
Entrez GeneID |
916 |
Swissprot |
P07766 |
clone |
4.00E+02 |
WB Predicted band size |
23kDa |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of CD3E expressed in E. Coli. |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Application |
WB |
1/500 - 1/2000 |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |