Cat.# |
TD-R381830 |
Product Name
|
CD163 Rabbit mAb
|
Gene ID
|
9332
|
SwissProt ID
|
Q86VB7
|
Gene Name
|
CD163
|
Alternative Names
|
CD163; CD163 antigen; CD163 molecule; SCARI1; sCD163; Soluble CD163
|
Background
|
Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subs/equent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human
|
Application
|
WB,IHC-P,IP
|
Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/30
|
Molecular Weight
|
Calculated MW: 125 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R02-9J1
|
Isotype
|
IgG
|
Immunogen
|
A synthesized peptide derived from human CD163
|
Purification
|
Affinity Chromatography
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|