Cat.# |
TD-R22825 |
Product Name
|
CD146 Rabbit mAb
|
Gene ID
|
4162
|
SwissProt ID
|
P43121
|
Gene Name
|
MCAM
|
Alternative Names
|
CD146; MUC18
|
Background
|
CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human,Rat
|
Application
|
WB,IHC-F,IHC-P,ICC/IF
|
Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
|
Molecular Weight
|
Calculated MW: 72 kDa; Obs/erved MW: 120 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R05-5A2
|
Isotype
|
IgG
|
Immunogen
|
A synthetic peptide of human CD146
|
Purification
|
Affinity Purified
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|