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CD133 (6H10) Mouse mAb

Cat.#	TD-200922
Product Name	CD133 (6H10) Mouse mAb
Gene ID	8842
SwissProt ID	O43490
Gene Name	PROM1
Alternative Names	Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.
Background	This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Field	Neuroscience
Product Categories	Primary antibody
Host	Mouse
Reactivity	Human
Application	WB
Dilution Ratio	WB: 1/500-1/1000
Molecular Weight	Calculated MW: 97 kDa; Obs/erved MW: 133 kDa
Clonality	Monoclonal Antibody
Clonality No.	6H10-F1-C11
Isotype	IgG2a
Immunogen	Purified recombinant human Prominin-1 protein fragments expressed in E.coli.
Purification	Affinity Purified
Conjugation	Unconjugated
Modification	Unmodified
Form	Liquid
Buffer System	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.