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CD Antibody
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Product
CD45
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WB
IHC-P
IHC-P
  • Catalog： TD-220898
  • Clonality： mAb
  • Application： WB, IHC-P
  • Synonyms： PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45
  • Specification：
    100ul 50ul 20ul
  • Prices：
    ¥2280
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CD45 Mouse mAb

Cat.# TD-220898
Product Name
CD45 Mouse mAb
Gene ID
5788
SwissProt ID
P08575
Gene Name
PTPRC
Alternative Names
PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Research Field
Immunology
Product Categories
Primary antibody
Host
Mouse
Reactivity
Human,Mouse
Application
WB,IHC-P
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
Molecular Weight
Calculated MW: 147 kDa; Obs/erved MW: 180-240kDa
Clonality
Monoclonal Antibody
Clonality No.
5D3A3
Isotype
IgG1
Immunogen
Purified recombinant fragment of human PTPRC expressed in E. Coli.
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.