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CD Antibody
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Product
Product
CD40 Mouse mAb
All
ICC/IF
  • Catalog： TD-220338
  • Clonality： mAb
  • Application： ICC/IF
  • Synonyms： CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
  • Specification：
    100ul 50ul
  • Prices：
    ¥2680
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CD40 Mouse mAb

Cat.# TD-220338
Product Name
CD40 Mouse mAb
Gene ID
958
SwissProt ID
P25942
Gene Name
CD40
Alternative Names
CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
Background
This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Research Field
Immunology
Product Categories
Primary antibody
Host
Mouse
Reactivity
Human
Application
ICC/IF
Dilution Ratio
IF: 1/50-1/200
Molecular Weight
-
Clonality
Monoclonal Antibody
Clonality No.
9G10
Isotype
IgG1
Immunogen
Purified recombinant fragment of CD40 expressed in E. Coli.
Purification
Ascitic Fluid
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Buffer System
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.