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抗体药类似物
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Research Grade Evinacumab
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  • Catalog： TD-HV176016
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： REGN1500,CAS:1446419-85-7
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Evinacumab

Catalog No. TD-HV176016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target ANG-5, Angiopoietin-like protein 3, ANGPT5, Angiopoietin-5, ANGPTL3, Angiopoietin-related protein 3
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q9Y5C1
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names REGN1500,CAS:1446419-85-7
Background Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
 SEC-HPLC detection for Research Grade Evinacumab.
TD-HV176016_2.jpg
Bioactivity
 
 Detects Human ANGPTL3 in direct ELISAs.