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抗体药类似物
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Research Grade Vantictumab
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  • Catalog： TD-HV162016
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： OMP-18R5,CAS:1345009-45-1
  • Specification：
    1mg
  • Prices：
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Research Grade Vantictumab

Catalog No. TD-HV162016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG2-lambda
Expression system Mammalian Cells
Clonality Monoclonal
Target FzE1, Frizzled-1, hFz1, Fz-1, FZD1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q9UP38
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names OMP-18R5,CAS:1345009-45-1
Background Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma.
Note For research use only. Not for use in clinical or therapeutic applications.