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Research Grade Nemolizumab

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Research Grade Nemolizumab

Catalog No.	TD-HV121016
Species reactivity	Human
Applications	Research Grade Biosimilar
Host species	Humanized
Isotype	IgG2-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	IL-31RA, Interleukin-31 receptor subunit alpha, IL31RA, hGLM-R, ZcytoR17, IL-31R-alpha, GPL, CRL3, Cytokine receptor-like 3, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like receptor, GLM-R, Gp130-like monocyte receptor
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G, purified from cell culture supernatant.
Accession	Q8NI17
Form	Liquid
Storage buffer	0.01M PBS,pH7.4.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	CIM331,CAS:1476039-58-3,Nemolizumab
Background	Nemolizumab (CIM331) is a humanized monoclonal antibody that targets the human interleukin-31 receptor a, preventing interleukin-31 (IL-31) from binding to its receptor and the subsequent signaling. Nemolizumab can help reduce itching and sleep disturbances, and it is being studied for atopic dermatitis (AD).
Note	For research use only. Not for use in clinical or therapeutic applications.

SEC-HPLC detection for Research Grade Nemolizumab.