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抗体药类似物
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Research Grade Latikafusp
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  • Catalog： TD-HV076016
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： Bispecificantibody,AMG256,AMG-256,AMG256,CAS:2552814-07-8
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Latikafusp

Catalog No. TD-HV076016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-lambda2
Expression system Mammalian Cells
Clonality Monoclonal
Target IL21R, NILR, Interleukin-21 receptor, IL-21R, IL-21 receptor, CD360, Novel interleukin receptor, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q9HBE5 & Q15116
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names Bispecificantibody,AMG256,AMG-256,AMG256,CAS:2552814-07-8
Background Latikafusp (AMG 256) is a bifunctional fusion protein comprising a PD-1-targeting antibody and IL-21 mutein designed to deliver IL-21 pathway stimulation to PD-1+ cells. Latikafusp is designed to prime and extend the activity of cytotoxic and memory T cells and induce anti-tumor immunity. Latikafusp has the potential for solid tumors research.Latikafusp may lead to the development of immunogenicity-mediated responses.
Note For research use only. Not for use in clinical or therapeutic applications.