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Research Grade Quilizumab

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Research Grade Quilizumab

Catalog No.	TD-HV064046
Species reactivity	Human
Applications	Research Grade Biosimilar
Host species	Humanized
Isotype	IgG1-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Ig epsilon chain C region, IGHE, Ig epsilon chain C region ND, Immunoglobulin heavy constant epsilon
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G, purified from cell culture supernatant.
Accession	P01854
Form	Liquid
Storage buffer	0.01M PBS,pH7.4.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	47H4,Anti-M1prime,MEMP1972A,RG-7449,CAS:1228538-47-3
Background	Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed IGHE/IgE, leading to IGHE/IgE switching and memory B cell depletion. Quilizumab has potential in asthma research.
Note	For research use only. Not for use in clinical or therapeutic applications.

SEC-HPLC detection for Research Grade Quilizumab.