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抗体药类似物
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Research Grade Dostarlimab
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  • Catalog： TD-HS870056
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： ANB-011,TSR-042,CAS:2022215-59-2
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Dostarlimab

Catalog No. TD-HS870056
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q15116
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names ANB-011,TSR-042,CAS:2022215-59-2
Background Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively.
Note For research use only. Not for use in clinical or therapeutic applications.

 

TD-HS870056_1.jpg
SEC-HPLC
 
 SEC-HPLC detection for Research Grade Dostarlimab.
TD-HS870056_2.jpg
Bioactivity
 
 Detects Human CD279/PDCD1/PD1 in indirect ELISAs.