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抗体药类似物
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Research Grade Dargistotug
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  • Catalog： TD-HS739086
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： CAS:2649362-29-6
  • Specification：
    1mg
  • Prices：
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Research Grade Dargistotug

Catalog No. TD-HS739086
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q495A1
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CAS:2649362-29-6
Background Dargistotug (M-6223) is a fully human IgG1 monoclonal antibody targeting TIGIT (T cell immune receptor with Ig domain and ITIM). TIGIT is an inhibitory immune checkpoint that promotes NK cell depletion and reduces the secretion of cytokines by binding to CD155 and other antibodies. It can also directly or indirectly inhibit effector T cells and upregulate Tregs cells, thereby exerting immunosuppression. Function.
Note For research use only. Not for use in clinical or therapeutic applications.