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抗体药类似物
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Research Grade Bexmarilimab
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  • Catalog： TD-HP617016
  • Clonality：
  • Application： Research Grade Biosimilar
  • Synonyms： FZD8-Fc,Frizzled8Fc,OMP-54F28,CAS:1391727-24-4
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Bexmarilimab

Catalog No. TD-HP617016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target MS-1 antigen, STAB1, FEEL-1, FEEL1, Stabilin-1, KIAA0246, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q9NY15
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer.
Note For research use only. Not for use in clinical or therapeutic applications.