Catalog No. |
TD-HP572016 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Host species |
Humanized(Lama/glama) |
Isotype |
VH-VH' |
Expression system |
Mammalian Cells |
Clonality |
Monoclonal |
Target |
Thrombospondin type-1 domain-containing protein 6, ADAMTSL5, ADAMTS-like protein 5, THSD6, ADAMTSL-5, ALB, Albumin |
Endotoxin level |
Please contact the lab for this information. |
Purity |
>95% purity as determined by SDS-PAGE. |
Purification |
Protein A/G, purified from cell culture supernatant. |
Accession |
Q6ZMM2 & P02768 |
Form |
Liquid |
Storage buffer |
0.01M PBS,pH7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names |
Bispecific,M-6495,CAS:2254082-79-4 |
Background |
Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life. |
Note |
For research use only. Not for use in clinical or therapeutic applications. |