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抗体药类似物
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Research Grade Ponezumab
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  • Catalog： TD-HP529016
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： PF-04360365,RN-1219,clone9TL,CAS:1178862-65-1
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Ponezumab

Catalog No. TD-HP529016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG2-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P05067
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names PF-04360365,RN-1219,clone9TL,CAS:1178862-65-1
Background Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease.
Note For research use only. Not for use in clinical or therapeutic applications.