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抗体药类似物
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Research Grade Forimtamig
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  • Catalog： TD-HP458026
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： rg6234,CAS:2649379-96-2
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Forimtamig

Catalog No. TD-HP458026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-lambda/kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target GPRC5D, G-protein coupled receptor family C group 5 member D, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q9NZD1 & P07766
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names rg6234,CAS:2649379-96-2
Background Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control .
Note For research use only. Not for use in clinical or therapeutic applications.