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抗体药类似物
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Research Grade Livmoniplimab
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  • Catalog： TD-HF977036
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： Bispecific,ABBV-151,ARGX-115,MHG-8,MHGARP-8,PR-1762844CAS:2412004-88-5
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Livmoniplimab

Catalog No. TD-HF977036
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB, GARP, Leucine-rich repeat-containing protein 32, Glycoprotein A repetitions predominant, D11S833E, Garpin, Transforming growth factor beta activator LRRC32, LRRC32
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P01137 & Q14392
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names Bispecific,ABBV-151,ARGX-115,MHG-8,MHGARP-8,PR-1762844CAS:2412004-88-5
Background Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors.
Note For research use only. Not for use in clinical or therapeutic applications.