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抗体药类似物
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Research Grade Luspatercept
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  • Catalog： TD-HF869016
  • Clonality：
  • Application： Research Grade Biosimilar
  • Synonyms： ACE-536,luspatercept–aamt,CAS:1373715-00-4
  • Specification：
    1mg
  • Prices：
    ¥询价
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Research Grade Luspatercept

Catalog No. TD-HF869016
Species reactivity Human
Applications Research Grade Biosimilar
Isotype Fusion - [ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)]2 - IGHG1 Fc (Fragment constant)
Expression system Mammalian Cells
Target GDF11, BMP-11, BMP11, Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession O95390
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names ACE-536,luspatercept–aamt,CAS:1373715-00-4
Background Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia.
Note For research use only. Not for use in clinical or therapeutic applications.