| Catalog No. |
TD-HF697016 |
| Species reactivity |
Human |
| Applications |
Research Grade Biosimilar |
| Host species |
Humanized |
| Isotype |
Fab-G1-kappa |
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
PFD, Adipsin, C3 convertase activator, Complement factor D, CFD, DF, Properdin factor D |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G, purified from cell culture supern atant. |
| Accession |
P00746 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS,pH7.4. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names |
AFD,Anti-fD,Anti-FACTORD,FCFD4514S,RG7417,CAS:1278466-20-8 |
| Background |
Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research. |
| Note |
For research use only. Not for use in clinical or therapeutic applications. |