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G Protein Monoclonal Antibodies
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Anti-Rheb Mouse Monoclonal Antibody
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  • Catalog： TD-26015
  • Clonality： 单克隆
  • Application： ELISA, WB, IHC
  • Synonyms：
  • Specification：
    100μl
  • Prices：
    ¥1600
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Anti-Rheb Mouse Monoclonal Antibody

Catalog Number:  TD-26015
Gene Symbol:  RHEB
Description:   Anti RheB Mouse Monoclonal Antibody
Background:   RheB (Ras Homolog Enriched in Brain) is an evolutionarily conserved member of the Ras-family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, RheB is widely expressed in other tissues and may be induced by growth factor stimulation. RheB has an important role in regulating the insulin/TOR signaling pathway. The mammalian target of rapamycin, mTOR, is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with translation and cell growth. The tuberin/hamartin (TSC2/TSC1) complex inhibits mTOR activity indirectly by inhibiting RheB via tuberin's GAP activity.
Immunogen:   Recombinant full length protein of RheB.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:100-1:5000 
WB: 1:100-1:2000 
IHC: 1:50-1:100
Concentration:   1 mg/ml
Host:   mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  RheB antibody recognizes RheB proteins of vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
 
Western blot:  
TD-26015.png
 
 Western blot analysis of RheB proteins. HEK-293 whole-cell lysate was used for Western blot.