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Recombinant Protein
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Human Tau pT217 Protein
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  • Article Number： TD-P-1013
  • Specification：
    50ug
  • Price：
    ¥4800
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Human Tau pT217 Protein

 

Product Name    Human Tau pT217 Protein
Cat.# TD-P-1013
Size 50ug
Protein Name TAU pT217 
Synonym DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU
Uniprot No.  P10636-8
Expression System  E. Coli
Compound Identity  6xHis at C-terminus
Full Length or Truncated  Full length
Molecular Weight  48.3 kDa 
Modification              Phosphorylation
Form   freeze-dried powde
Storage 2 days when stored at 2 to 8 °C after thawing
Up to 12 months when aliquoted and stored at -20 to -80 °C
Stability  ≥6 months 
Purity  ≥80% estimated by SDS-PAGE 
Supplied in 0.15 M Phosphate buffered saline, pH 7.4
Background
Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimers disease, frontotemporal dementia, and other tauopathies.